Brain Tumors 101: Radiation Therapy for the Brain Tumor Patient

BrainCancer.org presents our 10th video in our Brain Tumors 101 Series, “Radiation Therapy for the Brain Tumor Patient”. In this video, Dr. Charles Cobbs, Neurosurgeon and the Gregory Foltz Endowed Director of The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment at Swedish Neuroscience Institute, Seattle, WA, describes what radiation therapy is and […]

Brain Tumors 101 Series: “MGMT Methylation in Glioblastoma Brain Tumors”

BrainCancer.org presents its 6th video in the Brain Tumors 101 series, “MGMT Methylation in Glioblastoma Brain Tumors”. This is Part 2 of 2 on MGMT Methylation. Topics discussed in this video include: Temozolomide and impact on MGMT Methylated and Unmethylated glioblastoma brain tumors, prognosis for unmethylated vs methylated brain tumors, and details on how to […]

Immunocellular Therapeutics

Immunocellular Therapeutics Phase 3 ICT 107 Vaccine Clinical Trial for Glioblastoma Patients

ICT 107 is a vaccine for glioblastoma cancer stem cells.  This vaccine was developed by a company called ImmunoCellular Therapeutics, (https://www.imuc.com ) primarily by researchers at Cedars Sinai in Los Angeles.  https://virtualtrials.com/newsarticle.cfm?item=6107  This protocol has completed phase II testing and now it is open to a phase 3 randomized double blind control study for newly diagnosed glioblastoma.  […]

New High Throughput Screening Clinical Trial for Glioblastoma Brain Tumor Patients at Swedish, Seattle, WA

Swedish Medical Center in Seattle announces a clinical trial in humans for the treatment of glioblastoma, based on investigational high throughput screening of FDA-approved compounds targeting a patient’s own tumor stem cells. This trial will utilize a personalized approach for the treatment of tumor cells that have been screened against dozens of compounds, to find […]

UCLA researchers develop promising new combo treatment for deadly brain cancer

A recent article, http://www.newswise.com/articles/ucla-researchers-develop-a-likely-new-combo-treatment-for-the-deadliest-form-of-brain-cancer,  by my colleague Dr. Robert Prins at UCLA  in the prestigious journal Neuro Oncology has drawn significant attention.  Dr. Prins works with Dr. Linda Liau at UCLA developing immunotherapy approaches for treating glioblastoma.  Immunotherapy for cancer is a rapidly evolving field.  To the lay person it can be quite confusing.  There […]

GBM

Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors

Quite a bit of interest has resulted from a recent study performed by investigators at Mayo Clinic and UCSF with respect to various molecular categories of glioblastoma.  http://www.ncbi.nlm.nih.gov/pubmed/26061753  http://www.nejm.org/doi/full/10.1056/NEJMoa1407279 For the non-aficionado, these studies are very complex and confusing. If you have a PhD in molecular genetics you might understand it. I will attempt to […]