Newly Identified Brain Cancer Mutation Hopes To Aid Drug Development

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists     Duke University investigators have recently published and esoteric molecular genetics research finding that may increase our ability to understand the biology of pediatric intrinsic brainstem gliomas.  http://corporate.dukemedicine.org/news_and_publications/news_office/news/newly-identified-brain-cancer-mutation-will-aid-drug-development?utm_source=corporate.dukemedicine.org&utm_medium=rss&utm_campaign=RSS_news These are devastating […]

Dr. Charles Cobbs, The Gregory Foltz Endowed Director of the Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment at Swedish Neuroscience Institute Awarded $50,000 grant by The Musella Foundation

  Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   I am very excited to announce that my research group has been awarded a research grant from The Musella Foundation for Brain Tumor Research and Information, Inc., which will allow […]

New Brain Cancer Treatment Targets Tumor Hypoxia To Increase Benefits of Radiation Therapy

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists The most important aspect of treatment for glioblastoma is radiation treatment. Radiation probably has more of an impact on overall survival than surgery or chemotherapy. However, radiation works by breaking bonds of […]

Avastin rejected by EMA for Treatment of Glioblastoma

  Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   The advisers to the European Medicines Agency have recommended against expanding Avastin to treat glioblastoma.  http://www.pharmatimes.com/Article/14-05-25/EMA_advisors_reject_Avastin_for_brain_cancer.aspx While Avastin is used generously in the United States for glioblastoma, and can induced […]

Update on Phase II Trial by Immunocellular Therapeutics ICT 107 for Newly Diagnosed Glioblastoma

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   A recent presentation at the American Society for Clinical Oncology  (ASCO) meeting in Chicago this month shows some suggestion of efficacy of the ImmunoCellular Therapeutics immunotherapy vaccine ICT-107.   http://www.marketwatch.com/story/immunocellular-therapeutics-presents-updated-ict-107-phase-ii-data-in-patients-with-newly-diagnosed-glioblastoma-at-the-2014-asco-annual-meeting-2014-06-01  The vaccine […]

Autologous T cell Therapy for Cytomegalovirus as a Consolidative Treatment for Recurrent Glioblastoma

Charles S. Cobbs MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   Recently, a colleague of mine, Dr. Rajiv Khanna in Brisbane, Australia published an exciting paper in the journal Cancer Research.  http://cancerres.aacrjournals.org/content/early/2014/05/07/0008-5472.CAN-14-0296.abstract .  Dr. Khanna and his group have extensive experience in the esoteric […]

Brain Tumor Cells Penetrated by Tiny, Biodegradable Particles Carrying Genetic Instructions

    Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   Today we will touch upon a report out of Johns Hopkins that was published at the Journal of the American Chemical Society.  The title of the publication is Biodegradable Polymeric […]

Poliovirus used to treat recurrent glioblastoma

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   A recent study has gained quite a bit of press recently.  http://corporate.dukemedicine.org/news_and_publications/news_office/news/poliovirus-vaccine-trial-shows-early-promise-for-recurrent-glioblastoma/view .  This was a study performed out of Duke University and was presented as an abstract at the American Society […]

Researchers identify a code of ‘molecular switches’ in Glioblastoma stem cells

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   A recent manuscript published in the very prestigious journal Cell, by a group of researchers at Massachusetts General Hospital, has received some attention in the brain tumor community.  http://www.massgeneral.org/about/pressrelease.aspx?id=1693 This work is […]