Brain Tumors 101 Series: Surgical Options After A Brain Tumor Diagnosis

BrainCancer.org presents our 9th video in our Brain Tumors 101 series, ” Surgical Options After A Brain Tumor Diagnosis:”. In this video, Dr. Charles Cobbs, Neurosurgeon and the Gregory Foltz Endowed Director of The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment , discusses how surgical resections of brain tumors are approached by […]

Immunotherapy

Transplant drug could boost the power of brain tumor treatments

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   Investigators at the University of Michigan have made headway in one of the most difficult areas of immunotherapy for malignant glioma. http://www.uofmhealth.org/news/archive/201409/transplant-drug-could-boost-power-brain-tumor-treatments-u-m Immunotherapy is the use of a natural immune response […]

Gene Therapy Enhances Chemotherapy Tolerance and Efficacy in Glioblastoma Patients

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   Recently, investigators at the Fred Hutchinson Cancer Institute in Seattle published interesting findings in the Journal of Clinical Investigation, a highly regarded translational research journal. The title of their article was […]

Dr. Charles Cobbs
Neurosurgeon and The Gregory Foltz Endowed Director of the Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment at Swedish Neuroscience Institute

Genetic Markers in the Treatment of Brain Cancer

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   An article recently published in the journal Oncotarget has received quite a bit of publicity recently.   http://m.medicalxpress.com/news/2014-08-genetic-brain-cancer.html   The press release indicates that a new genetic test may change how brain cancers are treated. […]

New Brain Cancer Treatment Targets Tumor Hypoxia To Increase Benefits of Radiation Therapy

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists The most important aspect of treatment for glioblastoma is radiation treatment. Radiation probably has more of an impact on overall survival than surgery or chemotherapy. However, radiation works by breaking bonds of […]

Avastin rejected by EMA for Treatment of Glioblastoma

  Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   The advisers to the European Medicines Agency have recommended against expanding Avastin to treat glioblastoma.  http://www.pharmatimes.com/Article/14-05-25/EMA_advisors_reject_Avastin_for_brain_cancer.aspx While Avastin is used generously in the United States for glioblastoma, and can induced […]

Update on Phase II Trial by Immunocellular Therapeutics ICT 107 for Newly Diagnosed Glioblastoma

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   A recent presentation at the American Society for Clinical Oncology  (ASCO) meeting in Chicago this month shows some suggestion of efficacy of the ImmunoCellular Therapeutics immunotherapy vaccine ICT-107.   http://www.marketwatch.com/story/immunocellular-therapeutics-presents-updated-ict-107-phase-ii-data-in-patients-with-newly-diagnosed-glioblastoma-at-the-2014-asco-annual-meeting-2014-06-01  The vaccine […]

Autologous T cell Therapy for Cytomegalovirus as a Consolidative Treatment for Recurrent Glioblastoma

Charles S. Cobbs MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   Recently, a colleague of mine, Dr. Rajiv Khanna in Brisbane, Australia published an exciting paper in the journal Cancer Research.  http://cancerres.aacrjournals.org/content/early/2014/05/07/0008-5472.CAN-14-0296.abstract .  Dr. Khanna and his group have extensive experience in the esoteric […]

Researchers identify a code of ‘molecular switches’ in Glioblastoma stem cells

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   A recent manuscript published in the very prestigious journal Cell, by a group of researchers at Massachusetts General Hospital, has received some attention in the brain tumor community.  http://www.massgeneral.org/about/pressrelease.aspx?id=1693 This work is […]