New High Throughput Screening Clinical Trial for Glioblastoma Brain Tumor Patients at Swedish, Seattle, WA

Swedish Medical Center in Seattle announces a clinical trial in humans for the treatment of glioblastoma, based on investigational high throughput screening of FDA-approved compounds targeting a patient’s own tumor stem cells. This trial will utilize a personalized approach for the treatment of tumor cells that have been screened against dozens of compounds, to find […]

UCLA researchers develop promising new combo treatment for deadly brain cancer

A recent article, http://www.newswise.com/articles/ucla-researchers-develop-a-likely-new-combo-treatment-for-the-deadliest-form-of-brain-cancer,  by my colleague Dr. Robert Prins at UCLA  in the prestigious journal Neuro Oncology has drawn significant attention.  Dr. Prins works with Dr. Linda Liau at UCLA developing immunotherapy approaches for treating glioblastoma.  Immunotherapy for cancer is a rapidly evolving field.  To the lay person it can be quite confusing.  There […]

GBM

Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors

Quite a bit of interest has resulted from a recent study performed by investigators at Mayo Clinic and UCSF with respect to various molecular categories of glioblastoma.  http://www.ncbi.nlm.nih.gov/pubmed/26061753  http://www.nejm.org/doi/full/10.1056/NEJMoa1407279 For the non-aficionado, these studies are very complex and confusing. If you have a PhD in molecular genetics you might understand it. I will attempt to […]

Brain Tumors 101 Series: Surgical Options After A Brain Tumor Diagnosis

BrainCancer.org presents our 9th video in our Brain Tumors 101 series, ” Surgical Options After A Brain Tumor Diagnosis:”. In this video, Dr. Charles Cobbs, Neurosurgeon and the Gregory Foltz Endowed Director of The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment , discusses how surgical resections of brain tumors are approached by […]

Brain Tumors 101 Series: “MGMT Methylation in Glioblastoma Brain Tumors”

http://youtu.be/Ypp-VQEp42Y BrainCancer.org presents its 6th video in the Brain Tumors 101 series, “MGMT Methylation in Glioblastoma Brain Tumors”. This is Part 2 of 2 on MGMT Methylation. Topics discussed in this video include: Temozolomide and impact on MGMT Methylated and Unmethylated glioblastoma brain tumors, prognosis for unmethylated vs methylated brain tumors, and details on how […]

Dr. Charles Cobbs
Neurosurgeon and The Gregory Foltz Endowed Director of the Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment at Swedish Neuroscience Institute

Genetic Markers in the Treatment of Brain Cancer

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   An article recently published in the journal Oncotarget has received quite a bit of publicity recently.   http://m.medicalxpress.com/news/2014-08-genetic-brain-cancer.html   The press release indicates that a new genetic test may change how brain cancers are treated. […]

Newly Identified Brain Cancer Mutation Hopes To Aid Drug Development

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists     Duke University investigators have recently published and esoteric molecular genetics research finding that may increase our ability to understand the biology of pediatric intrinsic brainstem gliomas.  http://corporate.dukemedicine.org/news_and_publications/news_office/news/newly-identified-brain-cancer-mutation-will-aid-drug-development?utm_source=corporate.dukemedicine.org&utm_medium=rss&utm_campaign=RSS_news These are devastating […]

Dr. Charles Cobbs, The Gregory Foltz Endowed Director of the Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment at Swedish Neuroscience Institute Awarded $50,000 grant by The Musella Foundation

  Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   I am very excited to announce that my research group has been awarded a research grant from The Musella Foundation for Brain Tumor Research and Information, Inc., which will allow […]