Gene Therapy Enhances Chemotherapy Tolerance and Efficacy in Glioblastoma Patients

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   Recently, investigators at the Fred Hutchinson Cancer Institute in Seattle published interesting findings in the Journal of Clinical Investigation, a highly regarded translational research journal. The title of their article was […]

Dr. Charles Cobbs
Neurosurgeon and The Gregory Foltz Endowed Director of the Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment at Swedish Neuroscience Institute

Genetic Markers in the Treatment of Brain Cancer

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   An article recently published in the journal Oncotarget has received quite a bit of publicity recently.   http://m.medicalxpress.com/news/2014-08-genetic-brain-cancer.html   The press release indicates that a new genetic test may change how brain cancers are treated. […]

Progesterone and Treating Glioblastoma Multiforme

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   Recently a paper was published in the Journal of Steroid Biochemistry and Molecular Biology entitled “Anti-tumor effects of progesterone in human glioblastoma multiforme: Role of PI3K/Akt/mTOR signaling”.  http://news.emory.edu/stories/2014/06/labland_progesterone_for_brain_cancer/campus.html  This paper has received some attention amongst the […]

Avastin rejected by EMA for Treatment of Glioblastoma

  Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   The advisers to the European Medicines Agency have recommended against expanding Avastin to treat glioblastoma.  http://www.pharmatimes.com/Article/14-05-25/EMA_advisors_reject_Avastin_for_brain_cancer.aspx While Avastin is used generously in the United States for glioblastoma, and can induced […]

Autologous T cell Therapy for Cytomegalovirus as a Consolidative Treatment for Recurrent Glioblastoma

Charles S. Cobbs MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   Recently, a colleague of mine, Dr. Rajiv Khanna in Brisbane, Australia published an exciting paper in the journal Cancer Research.  http://cancerres.aacrjournals.org/content/early/2014/05/07/0008-5472.CAN-14-0296.abstract .  Dr. Khanna and his group have extensive experience in the esoteric […]

Brain Tumor Cells Penetrated by Tiny, Biodegradable Particles Carrying Genetic Instructions

    Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   Today we will touch upon a report out of Johns Hopkins that was published at the Journal of the American Chemical Society.  The title of the publication is Biodegradable Polymeric […]

Researchers identify a code of ‘molecular switches’ in Glioblastoma stem cells

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   A recent manuscript published in the very prestigious journal Cell, by a group of researchers at Massachusetts General Hospital, has received some attention in the brain tumor community.  http://www.massgeneral.org/about/pressrelease.aspx?id=1693 This work is […]

Ultrasound Waves in the Treatment of Brain Tumors

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   A recent press release stated that for the first time Swiss researchers have successfully treated a part of a recurrent glioma noninvasively using focused ultrasound waves. http://www.business-standard.com/article/news-ani/researchers-successfully-treat-brain-tumor-with-sound-waves-114040600163_1.html The use of focused […]