New High Throughput Screening Clinical Trial for Glioblastoma Brain Tumor Patients at Swedish, Seattle, WA

Swedish Medical Center in Seattle announces a clinical trial in humans for the treatment of glioblastoma, based on investigational high throughput screening of FDA-approved compounds targeting a patient’s own tumor stem cells. This trial will utilize a personalized approach for the treatment of tumor cells that have been screened against dozens of compounds, to find […]

GBM

Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors

Quite a bit of interest has resulted from a recent study performed by investigators at Mayo Clinic and UCSF with respect to various molecular categories of glioblastoma.  http://www.ncbi.nlm.nih.gov/pubmed/26061753  http://www.nejm.org/doi/full/10.1056/NEJMoa1407279 For the non-aficionado, these studies are very complex and confusing. If you have a PhD in molecular genetics you might understand it. I will attempt to […]

Part 2: Radiation Therapy for the Brain Tumor Patient

BrainCancer.org presents our 11th video in our Brain Tumors 101 Series, “Radiation Therapy for the Brain Tumor Patient Part 2”. In this video, Dr. Charles Cobbs, Neurosurgeon and the Gregory Foltz Endowed Director of The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment at Swedish Neuroscience Institute, Seattle, WA, describes linear beam radiation […]

Brain Tumors 101 Series: Surgical Options After A Brain Tumor Diagnosis

BrainCancer.org presents our 9th video in our Brain Tumors 101 series, ” Surgical Options After A Brain Tumor Diagnosis:”. In this video, Dr. Charles Cobbs, Neurosurgeon and the Gregory Foltz Endowed Director of The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment , discusses how surgical resections of brain tumors are approached by […]

The Blood Brain Barrier and Treatment of Brain Tumors

  A recent report in New Scientist describes what is being called a breakthrough in terms of scientists ability to open the blood brain barrier. http://www.newscientist.com/article/dn26432-brain-barrier-opened-for-first-time-to-treat-cancer.html#.VFppMiiZPZR What is the blood brain barrier and why is this important for glioblastoma patients, and is this truly a breakthrough?  First, it should be noted that most blood vessels in the […]

Gene Therapy Enhances Chemotherapy Tolerance and Efficacy in Glioblastoma Patients

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   Recently, investigators at the Fred Hutchinson Cancer Institute in Seattle published interesting findings in the Journal of Clinical Investigation, a highly regarded translational research journal. The title of their article was […]