New High Throughput Screening Clinical Trial for Glioblastoma Brain Tumor Patients at Swedish, Seattle, WA

Swedish Medical Center in Seattle announces a clinical trial in humans for the treatment of glioblastoma, based on investigational high throughput screening of FDA-approved compounds targeting a patient’s own tumor stem cells. This trial will utilize a personalized approach for the treatment of tumor cells that have been screened against dozens of compounds, to find […]

GBM

Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors

Quite a bit of interest has resulted from a recent study performed by investigators at Mayo Clinic and UCSF with respect to various molecular categories of glioblastoma.  http://www.ncbi.nlm.nih.gov/pubmed/26061753  http://www.nejm.org/doi/full/10.1056/NEJMoa1407279 For the non-aficionado, these studies are very complex and confusing. If you have a PhD in molecular genetics you might understand it. I will attempt to […]

Gene Therapy Enhances Chemotherapy Tolerance and Efficacy in Glioblastoma Patients

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   Recently, investigators at the Fred Hutchinson Cancer Institute in Seattle published interesting findings in the Journal of Clinical Investigation, a highly regarded translational research journal. The title of their article was […]

Newly Identified Brain Cancer Mutation Hopes To Aid Drug Development

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists     Duke University investigators have recently published and esoteric molecular genetics research finding that may increase our ability to understand the biology of pediatric intrinsic brainstem gliomas.  http://corporate.dukemedicine.org/news_and_publications/news_office/news/newly-identified-brain-cancer-mutation-will-aid-drug-development?utm_source=corporate.dukemedicine.org&utm_medium=rss&utm_campaign=RSS_news These are devastating […]

Researchers identify a code of ‘molecular switches’ in Glioblastoma stem cells

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   A recent manuscript published in the very prestigious journal Cell, by a group of researchers at Massachusetts General Hospital, has received some attention in the brain tumor community.  http://www.massgeneral.org/about/pressrelease.aspx?id=1693 This work is […]

Meet Dr. Charles Cobbs, Neurosurgeon & Director of The Ivy Center for Advanced Brain Tumor Treatment at Swedish Neuroscience Institute, Seattle, WA

Charles S. Cobbs, MD The Gregory Foltz, MD Endowed Director Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment Swedish Neuroscience Specialists   Dr. Cobbs is a neurosurgeon with particular interest in brain tumor biology. When he was an undergraduate at Princeton University, he was called by his parents to come home because his […]